drugs
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Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy
Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research…
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UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center
The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School…
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Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2
The coronavirus disease 2019 (COVID-19) pandemic has been ongoing since 2019, and it has tremendously affected the global healthcare system…
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Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model
In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory…
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High-risk prescribing practices associated with increased risk of disability among older adults
For many, good health and longevity is only achievable with the help of prescription drugs. However, researchers in Japan have…
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Cannabidiol for Parkinson’s disease symptom management
Parkinson’s disease (PD) is a neurodegenerative disorder caused by the loss of nerve cells in a part of the brain…
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Study reveals psychological benefits of statins
Statins have been hailed as a wonder drug; the cholesterol-lowering drugs have been prescribed to tens of millions of people…
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Report: Africa could have half of the world’s childhood cancer cases by 2050
Half of the global cases of childhood cancers could occur in Africa by 2050, with 56.3 cases per million people…
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Researchers explore COVID-19 vaccination in immunocompromised individuals
A review published in the Journal of Allergy and Clinical Immunology discusses the safety and efficacy of coronavirus disease 2019 (COVID-19) vaccination…
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Inflammation plays a key role in resolving pain
In a recent study published in the journal Science Translational Medicine, researchers explored the mechanisms underlying the transition from acute…
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Exercise increases levels of brain-derived neurotrophic factor which bolsters dopamine release
Exercise increases levels of a chemical involved in brain cell growth, which bolsters the release of the “feel good” hormone…
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Researchers help better understand the neuronal mechanisms of general anesthesia
In a paper recently published in Neuron, researchers from the group of Botond Roska at IOB reveal how different cell…
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Drug Overdose Deaths Hit an All-Time High in 2021, CDC Data Show
There were an estimated 107,622 drug overdose deaths in the U.S. in 2021, according to new data from the Centers…
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The potential role of the gut microbiome in modifying patient responses to statin therapy
In a recent study posted to Med, researchers discovered strong links between human gut microbiome makeup and statin on- and off-target…
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Study explores macromolecular viral entry inhibitors as broad-spectrum first-line antivirals with anti-SARS-CoV-2 activities
Various pandemics associated with viral pathogens have occurred in recent decades. The continuing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…
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Topical drugs may regress congenital giant nevi and prevent skin cancer
About one in 20,000 infants is born with what’s called a congenital giant nevus-;a huge, pigmented mole that may cover…
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Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells
In “proof of concept” experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed…
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Deep learning reveals genetic determinants of COVID-19-associated mortality
In a recent study posted to the medRxiv* preprint server, researchers applied deep learning methods and identified genetic variants linked…
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Targeting the mitochondrial pathway may be a potential strategy to halt prostate cancer growth
Hormone therapy is often used to treat prostate cancer that has spread to other parts of the body, but many…
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Lifesaving drug for opioid use disorder underutilized
Researchers at Washington University School of Medicine in St. Louis and Saint Louis University found that less than half of…
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Remdesivir shows no significant effect on patients with COVID-19 in Solidarity trial
Even as the coronavirus disease 2019 (COVID-19) continues to cause thousands of new cases and dozens of deaths each day,…
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How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets
In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a…
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Potential antiviral targets in SARS-CoV-2
In a recent study published in the iScience journal, researchers assessed potential targets in severe acute respiratory syndrome coronavirus 2…
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Applying a form of AI to sift through large amounts of biological data
Researchers at the University of Missouri are applying a form of artificial intelligence (AI) -; previously used to analyze how…
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Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs
Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset…
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Marine bioactive compounds against SARS-CoV-2
In the current era, viruses pose a significant threat to humans since they are capable of causing pandemics throughout the…
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Evaluation of the potential of new and repurposed TB vaccines
Scientists reported that tuberculosis (TB) is one the foremost causes of global mortality, especially in adults. In 2019, around 10 million…
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Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents
The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to…
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New drug combinations for obesity and diabetes may show greater efficacy than single therapy
Canadian and German researchers are teaming up to identify new drug combinations to treat people with obesity and Type 2…
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California opens Medicaid to older unauthorized immigrants
On May 1, California opened Medi-Cal to older immigrants residing in the state without legal permission. Unauthorized immigrants over age…
Read More » - UK-news
Alfie Boe took overdose as he went into ‘really dark place’ after marriage split
Exclusive: English tenor Alfie Boe has opened up about the depression he suffered when he split from Sarah, mum to…
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MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer
About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal…
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Talking therapies could be effective for treating depression in people with dementia
Feelings of anxiety and depression are common in people living with dementia and mild cognitive impairment, but the best way…
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CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit
CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today introduced its…
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‘Paralysed’ teen found slumped in toilet cubicle after possible drink spiking
Jess Insall has welcomed changes in the law which mean people face harsher sentences – but insists legislation needs to…
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Marine resources could be promising drug candidates against SARS-CoV-2 Omicron
A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the…
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Children prenatally exposed to antipsychotics do not have increased risk for neurodevelopmental disorders
Children of women who took antipsychotic medications late in their pregnancy did not demonstrate increased risk of neurodevelopmental disorders, according…
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US Rep. Gaetz’s diagnosis of what’s driving insulin costs misses the root cause
At the end of March, after the House passed a bill that would cap the cost of insulin at $35…
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Treatment for retinal vein occlusion yields long-lasting vision gains, study shows
New research shows that a treatment for retinal vein occlusion yields long-lasting vision gains, with visual acuity remaining significantly above…
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New insight into SARS-CoV-2 main protease opens door to new viral inhibitors
A recent study has revealed a full cycle of substrate cleavage for the main protease of the severe acute respiratory…
Read More » - Entrepreneurs
Is Turning Point Therapeutics Stock at a Turning Point?
One of the hottest stocks of 2020, Turning Point Therapeutics, Inc. (NASDAQ:TPTX) has suffered one of the biotech industry’s most…
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Study reveals a complexity to how the body “regulates the regulators” of the immune system
Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these…
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Mutated gene found in breast cancer recurrences may help tumors to become more aggressive
A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive…
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Scientists identify a way to reverse drug resistance by rewiring the inner workings of leukemia cells
Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a…
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Why cheap, older drugs that might treat covid never get out of the lab
In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the…
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New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity
Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind…
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Researchers identify 16 distinct cell populations in a key brain region for substance use disorders
In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct…
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Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2
In a recent study published in the International Journal of Molecular Sciences, researchers identified drugs inhibiting the entry of severe…
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Manipulating a specific gene from yeast could lead a new approach to combatting drug resistance
A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a…
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New chemical reaction creates a faster, simpler way of making tertiary amines for medicines
A University of Illinois at Urbana-Champaign research team has discovered a way to produce a special class of molecule that…
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_1b78fec41a5143afb6e7b9ad317023d2-620x480.jpg "US Rep. Gaetz’s diagnosis of what’s driving insulin costs misses the root cause 45")
