immunotherapy
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Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients
A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a…
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First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors
Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations…
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Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma
A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from γδ-T…
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Immunotherapy after bladder cancer surgery helps reduce cancer recurrence
Immunotherapy after surgery helped reduce cancer recurrence in patients with urothelial cancer of the bladder or other sites in the…
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Study identifies interleukin-6 as a potential target in refining cancer therapies
Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body’s immune system to kill cancer. These…
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T cell behavior informs metastatic melanoma outcomes
Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn’t work, and new…
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Targeting interleukin-6 could help reduce immune-related adverse events from immunotherapy
Researchers at The University of Texas MD Anderson Cancer Center have identified a novel strategy to reduce immune-related adverse events…
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Stem cell therapy prevents type 1 diabetes induced by anti-cancer drugs
Immune checkpoint inhibitors are widely used to treat a variety of cancers; however, one serious side effect is the onset…
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Discovery provides critical clues to why many immunotherapies trigger dangerous side effects
It’s not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing…
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Black and Hispanic people get the same benefits from CAR-T therapy as white patients
CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment…
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New data may change the standard of care for patients with advanced non-small cell lung cancer
The phase 2 clinical trial of a multi-center study known as the COAST clinical trial has demonstrated improved outcomes using…
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Researchers test an experimental treatment for metastatic cancer
Researchers at the University of Oklahoma are testing an experimental treatment for metastatic cancer focusing on pancreatic cancer. Metastasis, the…
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Newly discovered immune cell “soldier” could be a good target for immunotherapy
Despite the success of immunotherapy in helping many people with cancer, the majority of patients still do not respond to…
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New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity
Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind…
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A comprehensive rule book for the design of safe and efficient therapeutic cells
Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer. Compared to…
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Breakthrough finding reveals how male sex hormones contribute to cancer-related sex bias
Patients with cancers stemming from non-reproductive organs, such as bladder and liver cancer, have striking discrepancies in incidence, progression, response…
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Novel transdermal vaccine delivery for COVID-19 and cancer
Transdermal drug delivery is an alternative to oral or invasive drug delivery systems. This approach is associated with several advantages…
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Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients
Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation…
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Adding immunotherapy to chemotherapy before surgery improves outcomes for NSCLC patients
Adding the immunotherapy drug nivolumab to chemotherapy before surgery (neoadjuvant) for patients with operable non-small cell lung cancer (NSCLC) —…
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Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients
Several inflammatory and autoimmune conditions can be treated with significantly lower doses of interleukin 1 (IL-2) as compared to those…
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Combination immunotherapy reverses resistance to PD-1 inhibitors in patients with advanced melanoma
Patients with advanced melanoma whose cancer does not respond to treatment with widely used immunotherapy drugs known as PD-1 inhibitors…
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City of Hope’s late-breaking clinical trial data to be presented at AACR
Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, will present…
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